Government Biological Product (except Diagnostic) Manufacturing Contracts
NAICS 325414 · Biological Product (except Diagnostic) Manufacturing
Government biological product (except diagnostic) manufacturing contracts totaled $1.4B across 1,334 awards from FY2024 to FY2026. In FY2026, obligations were up 1021.7% versus FY2025; the Department of Health and Human Services was the largest buyer, accounting for $1.1B (80% of the total).
Key figures
In FY2026, contract obligations were $479,769,558 across 321 awards with activity that year, a change of +1021.7% from -$52,052,095 in FY2025. From FY2024 to FY2026, obligations totaled $1,417,671,309 across 1,334 awards.
- Obligated in FY2026
- $480M
- Awards in FY2026
- 321
- Change vs FY2025
- +1021.7%
- Total, FY2024 to FY2026
- $1.4B
Note: FY2026 ended on Sep 30, 2026. The Department of Defense publishes contract data with a 90-day delay, so FY2026 totals may still rise as late reports arrive.
Biological Product (except Diagnostic) Manufacturing contract spending by year
Federal biological product (except diagnostic) manufacturing contracts per fiscal year (October to September), under NAICS 325414. The table below lists the same numbers.
| Fiscal year | Obligated | Awards | Change |
|---|---|---|---|
| FY2026 | $479,769,558 | 321 | +1021.7% |
| FY2025 | -$52,052,095 | 576 | -105.3% |
| FY2024 | $989,953,847 | 871 | n/a |
About government biological product (except diagnostic) manufacturing contracts
Federal spending on biological product (except diagnostic) manufacturing contracts fell 52% from FY2024 ($990M) to FY2026 ($480M). FY2026 closed recently, and Defense Department contracts are reported up to 90 days late, so its total may still rise.
Spending is highly concentrated: the top 3 contractors account for 85% of the total. A few large firms win most of this work, so subcontracting can be the easiest way in.
The Department of Health and Human Services spends the most on biological product (except diagnostic) manufacturing contracts (80%), followed by the Department of Defense. The states with the most of this work are South Carolina, District of Columbia and Maryland.
NAICS 325414 (Biological Product (except Diagnostic) Manufacturing) is part of the Manufacturing sector.
Top biological product (except diagnostic) manufacturing government contractors
Companies ranked by contract dollars under NAICS 325414 (Biological Product (except Diagnostic) Manufacturing).
| # | Contractor | Obligated | Share |
|---|---|---|---|
| 1 | Advanced Technology International | $911,499,779 | 64.3% |
| 2 | Emergent Product Development Gaithersburg Inc. | $208,483,581 | 14.7% |
| 3 | Seqirus Inc | $87,835,198 | 6.2% |
| 4 | Meridian Medical Technologies, LLC | $72,927,012 | 5.1% |
| 5 | Sanofi Vaccines US Inc. | $65,973,000 | 4.7% |
| 6 | Seqirus USA Inc | $41,757,258 | 2.9% |
| 7 | Valneva USA, Inc. | $38,416,000 | 2.7% |
| 8 | Artemis Technologies Inc | $20,263,540 | 1.4% |
| 9 | Boehringer Ingelheim Animal Health USA Inc | $18,810,169 | 1.3% |
| 10 | Octapharma USA Inc. | $15,220,000 | 1.1% |
Agencies buying biological product (except diagnostic) manufacturing
Federal agencies ranked by contract dollars under NAICS 325414.
| # | Agency | Obligated | Share |
|---|---|---|---|
| 1 | Department of Health and Human Services | $1,140,084,653 | 80.4% |
| 2 | Department of Defense | $206,781,993 | 14.6% |
| 3 | Department of Agriculture | $59,106,711 | 4.2% |
| 4 | Department of Veterans Affairs | $28,640,436 | 2.0% |
| 5 | Department of Commerce | $905,745 | <0.1% |
| 6 | Department of Homeland Security | $794,530 | <0.1% |
| 7 | Department of State | $314,129 | <0.1% |
| 8 | Department of the Interior | $232,096 | <0.1% |
| 9 | Environmental Protection Agency | $209,418 | <0.1% |
| 10 | Smithsonian Institution | $52,127 | <0.1% |
Where biological product (except diagnostic) manufacturing contract work is performed
States ranked by contract dollars, using the place of performance on each award.
| # | State | Obligated | Share |
|---|---|---|---|
| 1 | South Carolina | $662,999,778 | 46.8% |
| 2 | District of Columbia | $261,254,072 | 18.4% |
| 3 | Maryland | $174,540,446 | 12.3% |
| 4 | North Carolina | $79,127,631 | 5.6% |
| 5 | Missouri | $74,922,826 | 5.3% |
| 6 | Pennsylvania | $63,232,223 | 4.5% |
| 7 | New Jersey | $18,986,995 | 1.3% |
| 8 | Georgia | $17,405,776 | 1.2% |
| 9 | California | $13,060,313 | 0.9% |
| 10 | New Hampshire | $10,091,845 | 0.7% |
Recent biological product (except diagnostic) manufacturing contract awards
The latest biological product (except diagnostic) manufacturing contracts, newest first. Each award ID links to its record on USAspending.gov.
| Start date | Recipient | Agency and description | Amount | Record |
|---|---|---|---|---|
| Sep 29, 2026 | Seqirus Inc | Department of Health and Human ServicesFORMULATION AND FILLING OF MF59-ADJUVANTED CELL-BASED A/HENAN/4-10CNIC/2022 (H3N8)-LIKE VACCINE AND CLINICAL TRIAL IMPLEMENTATION | $42,769,479 | 75A50126F61015 |
| Sep 28, 2026 | Lonza Walkersville, Inc | Department of Health and Human ServicesNIEHS: THIS ACQUISITION WILL PROVIDE 60 VIALS OF SPHEROID-QUALIFIED HUMAN LIVER CELLS FROM 30 MALE AND 30 FEMALE DONORS TO SUPPORT NCATS/NIEHS COMPLEMENT-ARIE RESEARCH FOCUSED ON DEVELOPING 3D MICROPH | $30,645 | 75N98026P01800 |
| Sep 28, 2026 | Lampire Biological Labs Inc | Department of Health and Human ServicesEO 14398: ANIMAL WHOLE BLOOD FOR BLOOD COMPATIBILITY TESTING | $34,870 | 75F40126P00297 |
| Sep 24, 2026 | Seqirus Inc | Department of Health and Human ServicesMANUFACTURE AND STABILITY STUDIES OF THIMEROSAL-FREE PANDEMIC INFLUENZA VACCINE MULTIDOSE VIALS (MDVS) | $2,148,912 | 75A50126F61014 |
| Sep 23, 2026 | Taconic Biosciences, Inc. | Department of Health and Human ServicesMOUSE MODEL, DISEASE INDUCTION, AND TREATMENT | $53,929 | 75N98026P01812 |
| Sep 23, 2026 | Fujifilm Biosciences Inc. | Department of Health and Human ServicesEO 14398 - PURCHASE OF HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED (HIPSC) CELLS. | $144,970 | 75F40126F19003 |
| Sep 22, 2026 | Bio-Rad Laboratories, Inc. | Department of Health and Human ServicesBIO-RAD DDPCR CONSUMABLES FOR CELL-FREE DNA ANALYSIS IN LUNG TRANSPLANT RESEARCH | $84,258 | 75N98026P01809 |
| Sep 16, 2026 | Indoor Biotechnologies, Inc. | Department of Health and Human ServicesHOUSE DUST MITE ANTIBODY SETS TO STANDARDIZE ALLERGEN EXTRACTS | $88,650 | 75F40126P00347 |
| Sep 14, 2026 | Integrated Dna Technologies, Inc. | Department of Health and Human ServicesINTEGRATED DNA TECHNOLOGIES INC:1107504 [26-009060] | $77,117 | 75N98026P01614 |
| Sep 14, 2026 | 10x Genomics, Inc. | Department of Health and Human ServicesNINDS: SUPPLY: CHROMIUM GEM-X SEQUENCING REAGENTS: N/A | $52,580 | 75N98026P01582 |
| Sep 14, 2026 | Zoetis Inc. | Department of Health and Human ServicesEO 14398: NAIHS OEHE RABIES VACCINES | $35,132 | 75H71026P00559 |
| Sep 10, 2026 | Life Technologies Corporation | Department of Health and Human ServicesNCATS: SUPPLY: HUMAN KINASE LENTIARRAY CRISPR LIBRARY: N/A | $24,143 | 75N98026P01605 |
| Sep 10, 2026 | Roche Diagnostics Corporation | Department of Health and Human Services26-005806 EXERCISE OPTION YEAR 2 09/01/2026 TO 08/31/2027 | $126,690 | 75N98026F00001 |
| Sep 10, 2026 | Lampire Biological Labs Inc | Department of Health and Human ServicesFRESH TURKEY, CHICKEN, GUINEA PIG, AND HORSE RED BLOOD CELLS EO14398 | $288,194 | 75D30126C21514 |
| Sep 8, 2026 | Bio-Techne Sales Corporation | Department of Health and Human ServicesRECOMBINANT RAT LEPTIN PROTEIN, CF | $34,273 | 75N98026P01528 |
| Sep 1, 2026 | Life Technologies Corporation | Department of Health and Human ServicesTHE PURPOSE OF THIS PURCHASE ORDER IS TO PROVIDE THE NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES (NIEHS) / DIVISION OF TRANSLATIONAL TOXICOLOGY (DTT) / THE MECHANISTIC TOXICOLOGY BRANCH (MMB) | $23,850 | 75N98026P01509 |
| Aug 27, 2026 | Bioivt, LLC | Department of Health and Human ServicesTHE MISSION OF THE NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES (NIDDK) IS TO CONDUCT AND SUPPORT MEDICAL RESEARCH AND RESEARCH TRAINING AND TO DISSEMINATE SCIENCE-BASED INFORMATIO | $19,995 | 75N98026P01445 |
| Aug 27, 2026 | Life Technologies Corporation | Environmental Protection AgencyCUSTOM TAQMAN PROBES WITH SPECIALIZED GENETIC TARGETS FOR APPROVED WATER RESEARCH PROJECTS | $19,780 | 68HERL26P0300 |
| Aug 26, 2026 | Norgen Biotek Corp | Department of Health and Human ServicesNHGRI - EXOSOME PURIFICATION RNA ISOLATION KITS | $16,811 | 75N98026P01422 |
| Aug 25, 2026 | American National Red Cross, the | Department of Veterans AffairsE014042 - BLOOD AND BLOOD PRODUCTS | $0 | 36C25226N0551 |
| Aug 25, 2026 | American National Red Cross, the | Department of Veterans AffairsE014042 - BLOOD AND BLOOD PRODUCTS | $0 | 36C25226N0550 |
| Aug 25, 2026 | American National Red Cross, the | Department of Veterans AffairsE014042 - BLOOD AND BLOOD PRODUCTS | $0 | 36C25226N0549 |
| Aug 24, 2026 | American National Red Cross, the | Department of Veterans AffairsE014042 - BLOOD AND BLOOD PRODUCTS | $0 | 36C25226N0548 |
| Aug 21, 2026 | Federal Prison Industries, Inc | Department of AgricultureBDM SERUM, HYCLONE SUPER LOW FBS MEDIA, NATIONAL BIO AND AGRO-DEFENSE FACILITY, MANHATTAN, KANSAS | $311,800 | 1232SA26P0463 |
| Aug 18, 2026 | Bio-Rad Laboratories, Inc. | Department of Health and Human ServicesLABS IN TSB BRANCH HAVE THE PRIMARY RESEARCH INTEREST ON THE CAUSE OF LUNG CANCER LUNG CANCER IS THE LEADING CAUSE OF CANCER-RELATED DEATHS WORLDWIDE. VISUALIZING PROTEIN EXPRESSION AND EVALUATING THE | $37,499 | 75N98026P01202 |
Open biological product (except diagnostic) manufacturing government bids
No open biological product (except diagnostic) manufacturing bids right now. Check the open bids page, which is updated daily from SAM.gov.
How to win government biological product (except diagnostic) manufacturing contracts
Federal biological product (except diagnostic) manufacturing contracts are posted on SAM.gov under NAICS 325414. Register your business free on SAM.gov with this code, watch for biological product (except diagnostic) manufacturing bids, and look for small business set-asides: many biological product (except diagnostic) manufacturing contracts for small business are reserved for small firms.
Explore government biological product (except diagnostic) manufacturing contracts by state, agency and contractor
- Department of Health and Human Services contracts
- Department of Defense contracts
- Department of Agriculture contracts
- Department of Veterans Affairs contracts
- Department of Commerce contracts
- Government contracts in South Carolina
- Government contracts in District of Columbia
- Government contracts in Maryland
- Government contracts in North Carolina
- Government contracts in Missouri
- Advanced Technology International government contracts
Frequently asked questions
- What NAICS code is used for government biological product (except diagnostic) manufacturing contracts?
- Federal biological product (except diagnostic) manufacturing contracts use NAICS 325414 (Biological Product (except Diagnostic) Manufacturing). List this code in your free SAM.gov registration to be found for these contracts.
- Who are the largest biological product (except diagnostic) manufacturing government contractors?
- By contract dollars under NAICS 325414 from FY2024 to FY2026, the largest were Advanced Technology International ($911M), Emergent Product Development Gaithersburg Inc. ($208M) and Seqirus Inc ($87.8M).
- Which agencies buy the most biological product (except diagnostic) manufacturing?
- From FY2024 to FY2026, the biggest buyers were the Department of Health and Human Services ($1.1B), the Department of Defense ($207M) and the Department of Agriculture ($59.1M).
- Where are government biological product (except diagnostic) manufacturing contracts performed?
- By contract dollars, the most federal biological product (except diagnostic) manufacturing work is performed in South Carolina ($663M), District of Columbia ($261M) and Maryland ($175M).
- Is federal spending on biological product (except diagnostic) manufacturing contracts growing?
- Federal biological product (except diagnostic) manufacturing contract obligations fell 52% from FY2024 ($990M) to FY2026 ($480M). FY2026 closed recently, and Defense Department contracts are reported up to 90 days late, so its total may still rise.
- Do I qualify as a small business for biological product (except diagnostic) manufacturing contracts?
- It depends on the SBA size standard for NAICS 325414, which is set either by average annual revenue or by number of employees. Check the current table of size standards on sba.gov before you bid on small business set-asides.
- What do I need to bid on government biological product (except diagnostic) manufacturing contracts?
- An active SAM.gov registration (free) with NAICS 325414 listed, the licenses and insurance your state requires for biological product (except diagnostic) manufacturing work, and examples of similar past work. Some solicitations also ask for specific certifications or security clearances.