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Government Medicinal and Botanical Manufacturing Contracts

NAICS 325411 · Medicinal and Botanical Manufacturing

Government medicinal and botanical manufacturing contracts totaled $13.6B across 408,435 awards from FY2024 to FY2026. In FY2026, obligations were down 9.9% from FY2025. The Department of Defense was the largest buyer, with $13.6B (100% of the total), while Amerisourcebergen Drug Corp received $13.4B (99% of the total).

Key figures

In FY2026, contract obligations were $4,469,267,889 across 114,849 awards with activity that year, a change of -9.9% from $4,960,131,180 in FY2025. From FY2024 to FY2026, obligations totaled $13,621,426,597 across 408,435 awards.

Obligated in FY2026
$4.5B
Awards in FY2026
114,849
Change vs FY2025
-9.9%
Total, FY2024 to FY2026
$13.6B

Note: FY2026 ended on Sep 30, 2026. The Department of Defense publishes contract data with a 90-day delay, so FY2026 totals may still rise as late reports arrive.

Medicinal and Botanical Manufacturing contract spending by year

Federal medicinal and botanical manufacturing contracts per fiscal year (October to September), under NAICS 325411. The table below lists the same numbers.

Medicinal and Botanical Manufacturing (NAICS 325411): contract obligations and awards by fiscal year
Fiscal yearObligatedAwardsChange
FY2026$4,469,267,889114,849-9.9%
FY2025$4,960,131,180120,739+18.3%
FY2024$4,192,027,528173,158n/a

About government medicinal and botanical manufacturing contracts

Federal spending on medicinal and botanical manufacturing contracts rose 7% from FY2024 ($4.2B) to FY2026 ($4.5B), peaking in FY2025. FY2026 closed recently, and Defense Department contracts are reported up to 90 days late, so its total may still rise.

Spending is highly concentrated: the top 3 contractors account for 99% of the total. A few large firms win most of this work, so subcontracting can be the easiest way in.

The Department of Defense spends the most on medicinal and botanical manufacturing contracts (100%), followed by the Department of the Interior. The states with the most of this work are Pennsylvania, Illinois and Michigan.

NAICS 325411 (Medicinal and Botanical Manufacturing) is part of the Manufacturing sector.

Top medicinal and botanical manufacturing government contractors

Companies ranked by contract dollars under NAICS 325411 (Medicinal and Botanical Manufacturing).

Top medicinal and botanical manufacturing government contractors, FY2024 to FY2026
#ContractorObligatedShare
1Amerisourcebergen Drug Corp$13,426,263,68698.6%
2Emergent Biodefense Operations Lansing LLC$63,335,8100.5%
3DMS Pharmaceutical Group Inc$59,387,1540.4%
4Cardinal Health, Inc.$15,384,7780.1%
5Animal Health International, Inc.$10,316,611<0.1%
6Fresenius Kabi, LLC$5,668,471<0.1%
7Atlantic Diving Supply, Inc.$4,782,845<0.1%
8Phoenix Textile Corporation$4,503,101<0.1%
9Altitude Technologies Inc.$3,516,433<0.1%
10Meridian Medical Technologies, LLC$3,487,825<0.1%

Agencies buying medicinal and botanical manufacturing

Federal agencies ranked by contract dollars under NAICS 325411.

Agencies buying medicinal and botanical manufacturing, FY2024 to FY2026
#AgencyObligatedShare
1Department of Defense$13,601,987,50799.9%
2Department of the Interior$10,298,211<0.1%
3Department of State$4,222,250<0.1%
4Department of Health and Human Services$3,844,969<0.1%
5Department of Veterans Affairs$892,374<0.1%
6Department of Agriculture$69,835<0.1%
7Department of Commerce$41,895<0.1%
8Department of Justice$39,556<0.1%
9Smithsonian Institution$30,000<0.1%

Where medicinal and botanical manufacturing contract work is performed

States ranked by contract dollars, using the place of performance on each award.

Where medicinal and botanical manufacturing contract work is performed, FY2024 to FY2026
#StateObligatedShare
1Pennsylvania$13,427,172,10198.6%
2Illinois$69,134,7380.5%
3Michigan$63,411,0050.5%
4Ohio$16,281,4610.1%
5Colorado$8,085,025<0.1%
6Missouri$6,635,587<0.1%
7Virginia$4,823,293<0.1%
8New Jersey$3,969,633<0.1%
9Oklahoma$3,498,033<0.1%
10New York$3,330,053<0.1%

Recent medicinal and botanical manufacturing contract awards

The latest medicinal and botanical manufacturing contracts, newest first. Each award ID links to its record on USAspending.gov.

Most recent contract awards, Medicinal and Botanical Manufacturing (NAICS 325411)
Start dateRecipientAgency and descriptionAmountRecord
Sep 24, 2026Animal Health International, Inc.Department of the InteriorFY27 DELIVERY ORDER FOR WILD HORSE AND BURRO HEALTH VACCINES$2,999,997140L0126F0123
Sep 18, 2026Miscellaneous Foreign AwardeesDepartment of StateCOVID VACCINES$16,22819DA2026P0971
Sep 16, 2026Polypeptide Laboratories San Diego, LLCDepartment of Health and Human ServicesMANUFACTURE OF GMP BATCH H105A PEPTIDE$601,00075N95026F00002
Sep 16, 2026Polypeptide Laboratories San Diego, LLCDepartment of Health and Human ServicesPROCESS DEVELOPMENT AND MANUFACTURE OF AZM152$315,00075N95026F00001
Sep 11, 2026Emes2 Pharmaceuticals, LLCDepartment of JusticeDISPOSAL OF EXPIRED/DAMAGED CONTROLLED SUBSTANCES$6,86015B21126P00000120
Jul 24, 2026DMS Pharmaceutical Group IncDepartment of Defense8512261082!INDOMETHACIN CAPSULES$12SPE2D226F3087
Jul 24, 2026DMS Pharmaceutical Group IncDepartment of Defense8512261120!LISINOPRIL TABLETS$3SPE2D226F3085
Jul 24, 2026DMS Pharmaceutical Group IncDepartment of Defense8512260931!ONDANSETRON HYDROCH$21SPE2D226F3080
Jul 23, 2026Cardinal Health, Inc.Department of Defense4572471768!NATIONAL PRIME VENDOR$21SPE2DU26F1Z23
Jul 23, 2026DMS Pharmaceutical Group IncDepartment of Defense4572477051!PHARM PRIME VENDOR FLEET$57SPE2DU26F1Z16
Jul 23, 2026DMS Pharmaceutical Group IncDepartment of Defense4572603399!PHARM PRIME VENDOR FLEET$81SPE2DU26F1Z12
Jul 23, 2026Cardinal Health, Inc.Department of Defense4572471348!PHARM PRIME VENDOR FLEET$1,826SPE2DU26F1Z10
Jul 23, 2026Cardinal Health, Inc.Department of Defense4572471349!PHARM PRIME VENDOR FLEET$3,318SPE2DU26F1Z09
Jul 23, 2026Cardinal Health, Inc.Department of Defense4572469913!PHARM PRIME VENDOR FLEET$420SPE2DU26F1Z05
Jul 23, 2026Cardinal Health, Inc.Department of Defense4572468813!PHARM PRIME VENDOR FLEET$399SPE2DU26F1Z04
Jul 23, 2026Cardinal Health, Inc.Department of Defense4572469915!PHARM PRIME VENDOR FLEET$7,209SPE2DU26F1Z03
Jul 23, 2026Cardinal Health, Inc.Department of Defense4572468814!PHARM PRIME VENDOR FLEET$1,082SPE2DU26F1Y99
Jul 23, 2026Cardinal Health, Inc.Department of Defense4572469916!PHARM PRIME VENDOR FLEET$123SPE2DU26F1Y97
Jul 23, 2026Cardinal Health, Inc.Department of Defense4572467825!PHARM PRIME VENDOR FLEET$1,191SPE2DU26F1Y95
Jul 23, 2026Cardinal Health, Inc.Department of Defense4572467824!PHARM PRIME VENDOR FLEET$670SPE2DU26F1Y94
Jul 23, 2026Cardinal Health, Inc.Department of Defense4572467823!PHARM PRIME VENDOR FLEET$30SPE2DU26F1Y91
Jul 23, 2026Cardinal Health, Inc.Department of Defense4572466955!PHARM PRIME VENDOR FLEET$2,068SPE2DU26F1Y89
Jul 23, 2026Cardinal Health, Inc.Department of Defense4572466954!PHARM PRIME VENDOR FLEET$411SPE2DU26F1Y88
Jul 23, 2026Cardinal Health, Inc.Department of Defense4572464945!PHARM PRIME VENDOR FLEET$50SPE2DU26F1Y87
Jul 23, 2026DMS Pharmaceutical Group IncDepartment of Defense4572957350!PHARM PRIME VENDOR FLEET$192SPE2DU26F1Y86

Open medicinal and botanical manufacturing government bids

No open medicinal and botanical manufacturing bids right now. Check the open bids page, which is updated daily from SAM.gov.

How to win government medicinal and botanical manufacturing contracts

Federal medicinal and botanical manufacturing contracts are posted on SAM.gov under NAICS 325411. Register your business free on SAM.gov with this code, watch for medicinal and botanical manufacturing bids, and look for small business set-asides: many medicinal and botanical manufacturing contracts for small business are reserved for small firms.

Frequently asked questions

What NAICS code is used for government medicinal and botanical manufacturing contracts?
Federal medicinal and botanical manufacturing contracts use NAICS 325411 (Medicinal and Botanical Manufacturing). List this code in your free SAM.gov registration to be found for these contracts.
Who are the largest medicinal and botanical manufacturing government contractors?
By contract dollars under NAICS 325411 from FY2024 to FY2026, the largest were Amerisourcebergen Drug Corp ($13.4B), Emergent Biodefense Operations Lansing LLC ($63.3M) and DMS Pharmaceutical Group Inc ($59.4M).
Which agencies buy the most medicinal and botanical manufacturing?
From FY2024 to FY2026, the biggest buyers were the Department of Defense ($13.6B), the Department of the Interior ($10.3M) and the Department of State ($4.2M).
Where are government medicinal and botanical manufacturing contracts performed?
By contract dollars, the most federal medicinal and botanical manufacturing work is performed in Pennsylvania ($13.4B), Illinois ($69.1M) and Michigan ($63.4M).
Is federal spending on medicinal and botanical manufacturing contracts growing?
Federal medicinal and botanical manufacturing contract obligations rose 7% from FY2024 ($4.2B) to FY2026 ($4.5B), peaking in FY2025. FY2026 closed recently, and Defense Department contracts are reported up to 90 days late, so its total may still rise.
Do I qualify as a small business for medicinal and botanical manufacturing contracts?
It depends on the SBA size standard for NAICS 325411, which is set either by average annual revenue or by number of employees. Check the current table of size standards on sba.gov before you bid on small business set-asides.
What do I need to bid on government medicinal and botanical manufacturing contracts?
An active SAM.gov registration (free) with NAICS 325411 listed, the licenses and insurance your state requires for medicinal and botanical manufacturing work, and examples of similar past work. Some solicitations also ask for specific certifications or security clearances.