Government Research and Development in Biotechnology (except Nanobiotechnology) Contracts
NAICS 541714 · Research and Development in Biotechnology (except Nanobiotechnology)
Government research and development in biotechnology (except nanobiotechnology) contracts totaled $7.4B across 2,421 awards from FY2024 to FY2026. Obligations were up 41.2% in FY2026 vs FY2025, and the Department of Health and Human Services was the largest buyer, accounting for $5.9B (79% of the total).
Key figures
In FY2026, contract obligations were $2,101,717,512 across 1,101 awards with activity that year, a change of +41.2% from $1,488,787,606 in FY2025. From FY2024 to FY2026, obligations totaled $7,446,579,881 across 2,421 awards.
- Obligated in FY2026
- $2.1B
- Awards in FY2026
- 1,101
- Change vs FY2025
- +41.2%
- Total, FY2024 to FY2026
- $7.4B
Note: FY2026 ended on Sep 30, 2026. The Department of Defense publishes contract data with a 90-day delay, so FY2026 totals may still rise as late reports arrive.
Research and Development in Biotechnology (except Nanobiotechnology) contract spending by year
Federal research and development in biotechnology (except nanobiotechnology) contracts per fiscal year (October to September), under NAICS 541714. The table below lists the same numbers.
| Fiscal year | Obligated | Awards | Change |
|---|---|---|---|
| FY2026 | $2,101,717,512 | 1,101 | +41.2% |
| FY2025 | $1,488,787,606 | 1,501 | -61.4% |
| FY2024 | $3,856,074,764 | 1,747 | n/a |
About government research and development in biotechnology (except nanobiotechnology) contracts
Federal spending on research and development in biotechnology (except nanobiotechnology) contracts fell 45% from FY2024 ($3.9B) to FY2026 ($2.1B). FY2026 closed recently, and Defense Department contracts are reported up to 90 days late, so its total may still rise.
Spending is spread widely: the top 3 contractors account for 33% of the total. No single company dominates, which leaves room for new and small contractors.
The Department of Health and Human Services spends the most on research and development in biotechnology (except nanobiotechnology) contracts (79%), followed by the Department of Defense. The states with the most of this work are South Carolina, California and Massachusetts.
NAICS 541714 (Research and Development in Biotechnology (except Nanobiotechnology)) is part of the Professional, Scientific, and Technical Services sector.
Top research and development in biotechnology (except nanobiotechnology) government contractors
Companies ranked by contract dollars under NAICS 541714 (Research and Development in Biotechnology (except Nanobiotechnology)).
| # | Contractor | Obligated | Share |
|---|---|---|---|
| 1 | Advanced Technology International | $1,768,358,047 | 23.7% |
| 2 | Albert B. Sabin Vaccine Institute, Inc. (The) | $356,898,734 | 4.8% |
| 3 | Amgen USA Inc | $345,768,625 | 4.6% |
| 4 | The Boeing Company | $324,826,313 | 4.4% |
| 5 | L3 Technologies, Inc. | $265,052,755 | 3.6% |
| 6 | Start2 Group, Inc. | $227,139,021 | 3.1% |
| 7 | PPD Development LP | $197,238,490 | 2.6% |
| 8 | Siga Technologies, Inc. | $167,743,809 | 2.3% |
| 9 | Shionogi Inc | $156,103,541 | 2.1% |
| 10 | Basilea Pharmaceutica International LTD, Allschwil | $147,371,637 | 2.0% |
Agencies buying research and development in biotechnology (except nanobiotechnology) services
Federal agencies ranked by contract dollars under NAICS 541714.
| # | Agency | Obligated | Share |
|---|---|---|---|
| 1 | Department of Health and Human Services | $5,876,570,876 | 78.9% |
| 2 | Department of Defense | $1,409,465,656 | 18.9% |
| 3 | Department of Veterans Affairs | $80,487,910 | 1.1% |
| 4 | National Aeronautics and Space Administration | $47,673,552 | 0.6% |
| 5 | Department of the Interior | $15,964,549 | 0.2% |
| 6 | Department of Agriculture | $7,443,373 | <0.1% |
| 7 | Department of Homeland Security | $3,774,582 | <0.1% |
| 8 | General Services Administration | $2,297,033 | <0.1% |
| 9 | Environmental Protection Agency | $1,182,405 | <0.1% |
| 10 | Department of Commerce | $839,904 | <0.1% |
Where research and development in biotechnology (except nanobiotechnology) contract work is performed
States ranked by contract dollars, using the place of performance on each award.
| # | State | Obligated | Share |
|---|---|---|---|
| 1 | South Carolina | $1,793,403,334 | 24.1% |
| 2 | California | $953,238,833 | 12.8% |
| 3 | Massachusetts | $777,613,963 | 10.4% |
| 4 | North Carolina | $500,558,406 | 6.7% |
| 5 | Maryland | $499,972,991 | 6.7% |
| 6 | District of Columbia | $396,745,720 | 5.3% |
| 7 | Alabama | $335,866,463 | 4.5% |
| 8 | Utah | $275,737,940 | 3.7% |
| 9 | Virginia | $269,389,512 | 3.6% |
| 10 | New Jersey | $259,700,017 | 3.5% |
Recent research and development in biotechnology (except nanobiotechnology) contract awards
The latest research and development in biotechnology (except nanobiotechnology) contracts, newest first. Each award ID links to its record on USAspending.gov.
| Start date | Recipient | Agency and description | Amount | Record |
|---|---|---|---|---|
| Sep 30, 2026 | Pharmacology Discovery Services Taiwan, LTD. | Department of Health and Human ServicesTHERAPEUTIC TESTING IN MURINE MODELS OF BACTERIAL INFECTION | $545,542 | 75N93026F00003 |
| Sep 30, 2026 | Organotherapeutics GMBH | Department of Health and Human ServicesEO 14398 HUMAN HINDBRAIN ORGANOIDS | $253,868 | 75F40126P00334 |
| Sep 30, 2026 | Brigham & Womens Hospital Inc | Department of Health and Human ServicesEO-14398-A LONG-TERM VASCULAR MPS TO ASSESS CYCLIC CARDIOVASCULAR TOXICITY OF ONCOLOGY DRUGS | $1,517,015 | 75F40126C00096 |
| Sep 30, 2026 | Texas a & M University | Department of Homeland SecurityMETAGENOMICS FOR BIOSURVEILLANCE | $600,000 | 70RSAT26FR0000079 |
| Sep 30, 2026 | University of Wisconsin System | Department of AgricultureSOYBEAN GENE EDITING SERVICE. | $40,000 | 12444326P0061 |
| Sep 29, 2026 | The Broad Institute, Inc | Department of Health and Human ServicesNIA - WHOLE GENOME SEQUENCING - NON-SEVERABLE | $215,100 | 75N98026P01944 |
| Sep 29, 2026 | Rector & Visitors of the University of Virginia | Department of Health and Human ServicesEO 14398 CRYO-ELECTRON MICROSCOPY (CRYO-EM) SERVICES | $82,760 | 75N98026P01763 |
| Sep 29, 2026 | Tranquil Clinical and Research Consulting Services LLC | Department of Health and Human ServicesFFP TASK ORDER FOR PROTON PUMP INHIBITOR PK STUDY FOR THE FDA'S CENTER FOR DRUG EVALUATION AND RESEARCH (CDER), OFFICE OF GENERIC DRUGS (OGD). | $1,227,674 | 75F40126F19001 |
| Sep 29, 2026 | University of Nebraska | Department of Homeland SecurityCOUNTERING NIHILISTIC VIOLENT EXTREMIST (NVE) THREATS - UNO NCITE | $1,838,383 | 70RSAT26FR0000072 |
| Sep 28, 2026 | Metabolon, Inc. | Department of Health and Human ServicesNIA: SERVICE: PLASMA METABOLON ASSAY FOR BALTIMORE LONGITUDINAL STUDY OF AGING (BLSA).: SEVERABLE | $164,205 | 75N98026P01908 |
| Sep 28, 2026 | Kaleo, Inc. | Department of Health and Human ServicesTHIS ACQUISITION WILL ALLOW BARDA TO INVEST PROJECT BIOSHIELD FUNDS FOR LATE-STAGE CLINICAL DEVELOPMENT, REGULATORY APPROVAL FOR 2-PAM AUTOINJECTORS (AS A DRUG/DEVICE COMBINATION PRODUCT) TO TREAT ORG | $96,058,494 | 75A50126C00010 |
| Sep 26, 2026 | Duke University | Department of Health and Human ServicesEO14398 - BROAD AGENCY ANNOUNCEMENT (BAA) FY26C1IP1 VALID APPROACHES TO INTEGRATING PATIENT SCIENCE INTO MEDICAL DEVICE STUDIES | $749,762 | 75F40126C00081 |
| Sep 26, 2026 | Simulations Plus Inc | Department of Health and Human ServicesTHE OVERARCHING OBJECTIVE IS TO ESTABLISH A QUANTITATIVE IN VITRO IN VIVO EXTRAPOLATION FRAMEWORK CAPABLE OF PREDICTING THE INFLUENCE OF FORMULATION COMPOSITION, DIGESTION BEHAVIOR, CHYLOMICRON BINDIN | $575,554 | 75F40126C00063 |
| Sep 25, 2026 | Lovelace Biomedical Research Institute | Department of Health and Human ServicesGLP REPEAT DOSE TOXICOLOGY STUDY FOR A LIVE-ATTENUATED RESPIRATORY VIRUS VACCINE. | $339,534 | 75N98026F00001 |
| Sep 25, 2026 | Utah State University | Department of Health and Human ServicesTASK A20 - INTERVENTIONAL AGENT TESTING AGAINST HIGH CONTAINMENT VIRUSES | $1,235,656 | 75N93026F00001 |
| Sep 25, 2026 | Institute for Clinical Pharmacodynamics, Inc. | Department of Health and Human ServicesC02 - PK-PD ANALYSIS OF MOUSE MODEL EFFICACY AND PK DATA FOR ANTIBACTERIAL COMPOUNDS | $111,080 | 75N93026F00001 |
| Sep 25, 2026 | The Research Foundation for the State University of New York | Department of Health and Human ServicesBAA FY26C1CP12: FDA, CENTER FOR DEVICES AND RADIOLOGICAL HEALTH (CDRH), ESTIMATION OF IN-VIVO TISSUE PROPERTIES USING CLINICAL MR THERMOMETRY DATA | $2,456,000 | 75F40126C00056 |
| Sep 25, 2026 | Oxos Medical Inc | Department of Health and Human ServicesDEVELOP AND VALIDATE THE OXOS X3, A PORTABLE X-RAY SYSTEM DESIGNED TO TRANSFORM TRAUMA RESPONSE BY BRINGING HOSPITAL-GRADE IMAGING DIRECTLY TO THE POINT OF NEED. THIS EFFORT WILL ELIMINATE CRITICAL TR | $9,574,161 | 75A50126C00011 |
| Sep 24, 2026 | Northwestern University | Department of Veterans AffairsBASE YR PERIOD WITH THREE ONE YR OPTION PERIODS SUPPORTING NORTHWESTERN UNI. SPECIALIZED RESEARCH FACILITY SERVICES. COVERING ANIMAL HOUSING, CARE, SEQUENCING, FLOW CYTOMETRY,..... AND OTHER CORE SERV | $64,500 | 36C25226C0046 |
| Sep 24, 2026 | Illumina, Inc. | Department of Health and Human ServicesILLUMINA DRAGEN GCP LVL 4 1-YEAR LICENSE | $113,004 | 75N98026P01619 |
| Sep 24, 2026 | Jackson Laboratory | Department of Health and Human ServicesTHE SCOPE OF THIS CONTRACT WILL BE TO PRODUCE, MAINTAIN, AND DISTRIBUTE ANEUPLOID MICE WITH A PRIMARY EMPHASIS ON MODELS OF HUMAN TRISOMY FOR CHROMOSOME 21. SEVERABLE | $749,999 | 75N94026C00003 |
| Sep 24, 2026 | Duke University | Department of Health and Human ServicesEO14398 - BROAD AGENCY ANNOUNCEMENT (BAA) FY26C1IP3 - ADVANCED RESEARCH AND DEVELOPMENT OF REGULATORY SCIENCE - CORE CLINICAL OUTCOME ASSESSMENT GRANT PROGRAM | $1,456,427 | 75F40126C00112 |
| Sep 24, 2026 | Rutgers the State University of New Jersey | Department of Health and Human ServicesEO 14398 BAA IDENTIFICATION AND PERFORMANCE ASSESSMENT OF MEDICAL DEVICES IN ELECTRONIC HEALTH RECORD DATA DEVELOPMENT OF A TRANSPARENT AND REPEATABLE FRAMEWORK TO ENHANCE MEDICAL DEVICE INTEGRATION I | $6,515,098 | 75F40126C00065 |
| Sep 24, 2026 | Iqvia Government Solutions Inc | Department of Health and Human ServicesOCCUPATIONAL EXPOSURE RISK MODELING FOR NEURODEGENERATIVE OUTCOMES: EO 14398 | $132,400 | 75D30126P21650 |
| Sep 24, 2026 | University of Wisconsin System | Department of Veterans AffairsBIOMEDICAL RESEARCH MODEL SERVICES AT THE UNIVERSITY WISCONSIN FOR THE PURCHASING, CARE AND FEEDING OF MICE FOR HER VA FUNDED RESEARCH TITLE: FABP7 AS A THERAPEUTIC TARGET IN TRAUMATIC BRAIN INJURY UW | $37,405 | 36C25226C0055 |
Open research and development in biotechnology (except nanobiotechnology) government bids
No open research and development in biotechnology (except nanobiotechnology) bids right now. Check the open bids page, which is updated daily from SAM.gov.
How to win government research and development in biotechnology (except nanobiotechnology) contracts
Federal research and development in biotechnology (except nanobiotechnology) contracts are posted on SAM.gov under NAICS 541714. Register your business free on SAM.gov with this code, watch for research and development in biotechnology (except nanobiotechnology) bids, and look for small business set-asides: many research and development in biotechnology (except nanobiotechnology) contracts for small business are reserved for small firms.
Explore government research and development in biotechnology (except nanobiotechnology) contracts by state, agency and contractor
- Department of Health and Human Services contracts
- Department of Defense contracts
- Department of Veterans Affairs contracts
- National Aeronautics and Space Administration contracts
- Department of the Interior contracts
- Government contracts in South Carolina
- Government contracts in California
- Government contracts in Massachusetts
- Government contracts in North Carolina
- Government contracts in Maryland
- Advanced Technology International government contracts
- Boeing government contracts
- L3 Technologies government contracts
Frequently asked questions
- What NAICS code is used for government research and development in biotechnology (except nanobiotechnology) contracts?
- Federal research and development in biotechnology (except nanobiotechnology) contracts use NAICS 541714 (Research and Development in Biotechnology (except Nanobiotechnology)). List this code in your free SAM.gov registration to be found for these contracts.
- Who are the largest research and development in biotechnology (except nanobiotechnology) government contractors?
- By contract dollars under NAICS 541714 from FY2024 to FY2026, the largest were Advanced Technology International ($1.8B), Albert B. Sabin Vaccine Institute, Inc. (The) ($357M) and Amgen USA Inc ($346M).
- Which agencies buy the most research and development in biotechnology (except nanobiotechnology)?
- From FY2024 to FY2026, the biggest buyers were the Department of Health and Human Services ($5.9B), the Department of Defense ($1.4B) and the Department of Veterans Affairs ($80.5M).
- Where are government research and development in biotechnology (except nanobiotechnology) contracts performed?
- By contract dollars, the most federal research and development in biotechnology (except nanobiotechnology) work is performed in South Carolina ($1.8B), California ($953M) and Massachusetts ($778M).
- Is federal spending on research and development in biotechnology (except nanobiotechnology) contracts growing?
- Federal research and development in biotechnology (except nanobiotechnology) contract obligations fell 45% from FY2024 ($3.9B) to FY2026 ($2.1B). FY2026 closed recently, and Defense Department contracts are reported up to 90 days late, so its total may still rise.
- Do I qualify as a small business for research and development in biotechnology (except nanobiotechnology) contracts?
- It depends on the SBA size standard for NAICS 541714, which is set either by average annual revenue or by number of employees. Check the current table of size standards on sba.gov before you bid on small business set-asides.
- What do I need to bid on government research and development in biotechnology (except nanobiotechnology) contracts?
- An active SAM.gov registration (free) with NAICS 541714 listed, the licenses and insurance your state requires for research and development in biotechnology (except nanobiotechnology) work, and examples of similar past work. Some solicitations also ask for specific certifications or security clearances.