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Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA)

Solicitation · Department of Health and Human Services · Responses due Dec 2, 2026

Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA) is a solicitation posted on SAM.gov by Department of Health and Human Services (Advanced Research Projects Agency for Health (Arpa-H)) on Oct 29, 2026, under NAICS 541715 (Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)). No small business set-aside is listed. Responses are due Dec 2, 2026.

Notice type
Solicitation
Agency
Department of Health and Human Services
Office
National Institutes of Health / Advanced Research Projects Agency for Health (Arpa-H)
Solicitation number
ARPA-H-SOL-26-163
Industry (NAICS)
541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
Set-aside
None listed
Place of performance
Not stated
Posted
Oct 29, 2026
Responses due
Dec 2, 2026 (31 days left)

The full description, attachments and response instructions are on SAM.gov: read this notice on SAM.gov. To respond you need an active SAM.gov registration, which is free.

What this solicitation means

A solicitation (an RFP, RFQ or IFB) asks businesses to submit bids, quotes or proposals. Your response is an offer the agency can accept and turn into a contract.

  1. Read the full solicitation and every attachment on SAM.gov, including the scope of work and evaluation criteria.
  2. Confirm you are eligible: active SAM.gov registration, the NAICS size standard and any set-aside.
  3. Submit questions to the contracting officer before the question deadline, if there is one.
  4. Prepare your response exactly as instructed and submit it before the deadline.

Who wins research and development in the physical, engineering, and life sciences (except nanotechnology and biotechnology) government contracts

Federal agencies obligated $133B on contracts under NAICS 541715 from FY2024 to FY2026, including $43.8B in FY2026. The largest contractors in this industry, possible competitors or teaming partners for this bid:

  1. Fluor Marine Propulsion, LLC: $11.3B
  2. California Institute of Technology: $6.6B
  3. The Johns Hopkins University Applied Physics Laboratory LLC: $5.5B
  4. Lockheed Martin Corporation: $4B
  5. The Aerospace Corporation: $3.9B

Recent research and development in the physical, engineering, and life sciences (except nanotechnology and biotechnology) contract awards

Recent contract awards under NAICS 541715
Start dateRecipientAgency and descriptionAmountRecord
Sep 30, 2026Toxcel LLCDepartment of TransportationTITLE: IMPAIRED DRIVING TECHNICAL ASSISTANCE PARSID: 931 PURPOSE: THE PURPOSE OF THIS TASK ORDER IS TO PROVIDE TECHNICAL ASSISTANCE TO STATES AND LOCAL PROGRAMS ON THE IMPLEMENTATION AND OPERATION OF $500,000693JJ926F00142N
Sep 30, 2026Dynamis, Inc.Department of Homeland SecurityINTERMODAL SECURITY TRAINING AND EXERCISE PROGRAM SUPPORT SERVICES$862,65370T04026F5900N001
Sep 30, 2026Ist Research, LLCGeneral Services AdministrationIST PULSE SBIR III DO 58 DARPASAF$9,517,43247QFCA26F0037
Sep 30, 2026Asrc Consulting & Environmental Services, LLCDepartment of EnergyALASKA NORTH SLOPE GAS HYDRATE PRODUCTION TEST PROJECT 2.0$18,510,00089243326CFE000107
Sep 30, 2026Air-Lock, IncorporatedNational Aeronautics and Space AdministrationTASK ORDER 10 - SUIT ANCILLARY HARDWARE PROCUREMENT FOR OCSS SUIT USE ON HLS PART V$401,18780NSSC26F0115

More: government research and development in the physical, engineering, and life sciences (except nanotechnology and biotechnology) contracts · NAICS 541715

HHS contract spending

The Department of Health and Human Services obligated $76B on contracts from FY2024 to FY2026. Its largest contractors were General Dynamics Information Technology, Inc., Advanced Technology International, Maximus Federal Services, Inc.. What it buys most: computer systems design services, administrative management and general management consulting services, other computer related services.

See Department of Health and Human Services contracts: top contractors, what it buys and recent awards.

Similar open bids: research and development in the physical, engineering, and life sciences (except nanotechnology and biotechnology)

More open government contracts

Guides for this bid

Frequently asked questions

When is the response deadline for ARPA-H-SOL-26-163?
Responses are due Dec 2, 2026. Always confirm the date and time zone in the notice on SAM.gov, since agencies sometimes extend deadlines with an amendment.
Who can respond to Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA)?
No set-aside is listed, so any responsible business registered in SAM.gov can respond, large or small. Registration is free.
Who usually wins research and development in the physical, engineering, and life sciences (except nanotechnology and biotechnology) government contracts?
Under NAICS 541715, the largest federal contractors from FY2024 to FY2026 were Fluor Marine Propulsion, LLC ($11.3B), California Institute of Technology ($6.6B), The Johns Hopkins University Applied Physics Laboratory LLC ($5.5B).

Source: SAM.gov Contract Opportunities, last checked Oct 30, 2026. Independent website. Not affiliated with any government agency.